Morphine Treatment

• Help reduce anxiety, irritability
• Relieve symptoms such as symptoms of sweating, and runny nose
• A safe alternative or complement to pharmacological treatments
• Relieve symptoms such as dizziness and hearing loss
• Overcome morphine addiction

1. Touchscreen.

2. Adjustable frequency settings: Select any frequency from 1 Hz to 999 Hz to suit your requirements.

3. Display lock feature: Lock the screen to avoid unintended adjustments when the device is in your pocket.

4. Intuitive design for easy use.

5. Type-C USB connection.

6. Lightweight and portable, making it convenient to take anywhere.

7. Achieves up to 90% treatment efficiency.

Simple Operational Steps:

Attach the device to the nasal applicator according to the instructions.

Choose the preferred output mode: Pulse or Continuous.

Set the treatment duration and power level to match your requirements.

Begin the therapy by following the user guidelines provided.

Clinical Study:

Sixty patients with a history of drug abuse ranging from 1 to 2 years were selected from the Zhengzhou Public Security Bureau Detoxification Center. After physiological detoxification, they began experiencing prolonged withdrawal symptoms within 7-10 days. The participants, aged 18 to 40 with an average age of 32, included 20 females and 40 males. They were randomly divided into three groups, each comprising 20 individuals. Groups 1 and 2 received laser treatment, while Group 3 served as the control. The treatment group uniformly used the Wuhan Koz low-frequency treatment device with a wavelength of 650nm and adjustable output power ranging from 0 to 5 mW. Special disposable puncture needles, optical fibers, and a laser nasal irradiation treatment head were utilized for intravascular and nasal irradiation.

Treatment Methods:

Groups 1 and 2 received low-intensity laser blood therapy. Group 1 underwent intravascular low-intensity laser irradiation therapy (ILILIT), where a specially designed disposable optical fiber was inserted into the patient's elbow, head, or important veins for circulation irradiation. The power ranged from 2 to 2.5 mW, with a power density of 2.54 mW/mm² to 3.18 mW/mm², lasting 60 minutes per session.

The dosage ranged from 9.17J/mm² to 11.45J/mm². Each patient received one session per day for 10 days per course of treatment. Group 2 received low-intensity laser nasal irradiation therapy. The laser was delivered into both nostrils using a special nasal cap. The power ranged from 4 to 5mW, with a power density of 1.27mW/mm² to 1.59mW/mm², irradiating each nostril for 45 minutes per session. The total dosage for both nostrils ranged from 9.17J/mm² to 11.45J/mm². Treatment was administered once daily for 10 days per course.

The control group (Group 3) received no special treatment after 7-10 days of physiological detoxification. Only symptomatic medication was provided when certain withdrawal symptoms were severe (e.g., severe insomnia, diarrhea, anxiety).

Physiological and biochemical indicators were measured in all three groups before and after treatment or observation (control group). Data were statistically analyzed using Microsoft Excel and t-tests.

The research results indicate that low-intensity laser blood therapy significantly improved the withdrawal symptoms of drug abusers, with various physiological and biochemical indicators showing improvement. Patients generally reported improvements such as reduced insomnia, alleviated diarrhea, improved anxiety, reduced bodily pain, and decreased coughing. Patients in the treatment groups transitioned from initial resistance to positive cooperation and friendly attitudes.

This study was conducted based on animal experiments, and the laser doses used were within the safety threshold, with no toxic side effects observed during treatment. Both treatment methods achieved the expected results. Nasal irradiation is non-invasive, safe, and reliable, allowing for home use. Prolonged symptoms persist after detoxification, but regular treatment with a self-owned device can alleviate symptoms and prevent relapse effectively.

objects: Total of 40 drug addicts, including 20 men and 20 women, the age between 18-40, and the drug addiction time is 1-2 years since getting rid of the drug and treatment for 7-10 days, 40 drug addicts show Protracted Withdrawal Symptoms to the different extent.

Device: WuHan COZING MEDICAL produced COZING-BQ06A,and the nasal laser is 650nm wavelength,the output power is 0-5rnw continuously adjustable.

Methods: Randomly divide 40 addicts into 2 groups.

Group A: Adopt the COZING-BQ06A nasal laser therapy. Use this special laser nasal applicator. and insert it into the addict's right and left nasal cavity for irradiation therapy. Power 4～5mW, power density 1.2~1.597mW/mm², each treatment time is 45 minutes. The laser irradiation dose is 3.43---4.29 J/mm2, the total irradiation time is 90 minutes for both nasal cavities and the total dose is 6.86-8.89 J/mW. Irradiation once a day, 10 days for a course of treatment.

Group B: the comparison group.

The drug rehabilitation center treatment methods, give the addicts sleeping pills, painkillers, and so on as the addict's symptoms, generally without other treatment.

Evaluation Standards:

According to the severity of drug addiction recurrence symptoms, the score is higher, the symptom is more severe.

Conclusion

After a course of treatment (10 days) . Compared with Group B, the Protracted withdrawal symptoms were significantly improved in the nasal irradiation group, and the average total score was significantly decreased. See table:

Most of the literature shows that the animal morphine cut-off response was caused by an increase in norepinephrine release from the brainstem locus coeruleus.Subsequent subcutaneous morphine withdrawal symptoms in experimental animals indicate Vegetative nerve functional disturbance

The clinical observation shows that: one of the most unbearable symptoms is the sleep disorder when the heroin addicts try to get rid of the drug, and it is also a major factor in relapse. Sleep regulation is not only affected by the nervous system, endocrine system, and psychological factors but is also related to cytokine content. The data show that interleukin-1 (1L1), interleukin-2 (1L-2), and tumor necrosis factor (TNF) are important immunoregulatory and effectors, and all three have a role in regulating sleep.

Low-intensity lasers have the function of improving blood rheological parameters, increasing red blood cell deformability, and regulating immune, endocrine, and nervous system functions. Therefore, the inhibitory effect of laser on the morphine cut-off response may be achieved by reducing the sympathetic nervous system tension.

Low-intensity laser hematology uses low-intensity laser irradiation on circulating blood indirectly, with safe and non-toxic side effects. In particular, nasal irradiation can be used in homes and it has a definite curative effect on the treatment of protracted withdrawal symptoms. Frequent use can make withdrawal symptoms gradually disappear and has a significant effect on anti-relapse therapy.