Class IV Laser Therapy

1. Powerful Performance: Reduces the time required for treatments.

2. Customizable Therapy: Treatment duration and power levels can be adjusted at any time.

3. Ergonomic Design: The device provides a 3-second output for each adjustment made.

4. Tailored Options: For 904nm/830nm/450nm wavelengths or power levels of 5W/10W/35W/75W, as well as rental options, please contact us directly.

5. Compact and Elegant: Easy to carry with a sophisticated look, includes a free treatment protocol.

6. Complete Package: 1x Low-level cold laser device for pain relief, 1x Power adapter, 1x Carrying case, 1x User manual, 1x Warranty card, 2x Safety glasses with case, 1x Stand

Class IV laser therapy reduces nerve sensitivity by decreasing bradykinin, a chemical that causes pain.It normalizes ion channels (cell gatekeepers) and releases endorphins (the body's natural painkillers) and enkephalins (related to endorphins), resulting in pain relief and affecting certain nerve fibers to alleviate pain.

Laser increases ATP, which is stored energy (ATP stands for adenosine triphosphate).Laser also causes dilation of arteries and veins around the injury, helping to clear damaged cellular debris and increase the supply of nutrients and oxygen.White blood cell activity is enhanced, leading to a faster repair process.

Additionally, some molecules that increase inflammation are reduced, while beneficial antioxidants such as superoxide dismutase are increased. Photons emitted by the laser deeply penetrate tissues, accelerating cell reproduction and growth. Exposure to the laser results in faster repair of tendon, ligament, nerve, and muscle cells.

Laser increases the formation of new capillaries in damaged tissue, speeding up the healing process and quickly closing wounds.

The present study investigates the synergistic effects of superpulsed 904 nm laser-mediated PBM combined with CoQ10 on full-thickness burn wound healing in experimental rats, and further explores the underlying tissue repair mechanisms by analyzing markers pertaining to redox homeostasis, bioenergetics, cell survival, calcium and cellular proliferation signaling.

Materials and methods

Twenty-four animals were randomized into 4 sub-groups comprising 6 animals in each: burn control group, 904 nm superpulsed laser PBM treatment group, CoQ10 treatment group and combined treatment group. The animals of the control group were not given any treatment. PBM treatment was performed using a Ga-As diode superpulsed 904 nm laser (COZING-T05) , duration 10 min (once daily), to deliver a light spot centered on a transdermal burn wound at the dorsal surface of rats, as explained earlier.



Conclusion

Collectively, the findings from the present study demonstrate synergism in combination treatment of 904 nm superpulsed laser PBM and topical application of CoQ10 in augmenting burn wound healing. The dual treatment significantly reducing oxidative stress and enhancing cellular proliferation, collagen deposition and bioenergetics activation, which might have occurred owing to different target molecules of both the healing modalities. The novel multi-target therapeutic approach using PBM with NIR superpulsed 904 nm laser and CoQ10 might positively influence the downstream signaling cascade, which in turn augment burn wound healing.